Portfolio Companies

Imagine Devices is a next generation feeding tube for use in prematurely-born babies.

IMAGExRAY PedScan, is a patented mobile fluoroscopic imaging system specifically designed for the diagnosis and treatment of dysphagia and for conducting Esophagram tests in pediatric patients.

SmoVac is a single use detachable suction device that provides efficient intraoral aerosol mitigation with less noise while providing without obstructing the surgeon’s field of sight

Ultration is a handheld battery operated ultrasound device that has AI software technology that provides an automated constipation score.

TNC Medical Solutions is developing a G-tube reinsertion system to improve patient care and procedural outcomes.

BSD SAGI is a patented delivery system for inhaling medicines, making the treatment more effective and more friendly for both parents and children,

SageSpectra develops pediatric wearable patches for non-invasive, real-time monitoring of temperature and StO2, supporting early detection and improved clinical outcomes for infants and neonates

Kilele Health designed a wearable SunVida system which monitors Phe levels real-time around the clock with a small wearable sensor.

Sprout is the first balloon-expandable RV-PA conduit to replace right ventricular outflow tracts for congenital heart disease (CHD) patients. These can mechanically grow with the patient, reducing surgical re-interventions by 75%.

Exhalos is a neonatal medical device company focused on early detection of necrotizing enterocolitis (NEC) in newborns, using a breath-based monitoring device

Enhance Diagnostics develops noninvasive breath tests to monitor ammonia levels in pediatric Urea Cycle Disorder patients, enabling early intervention and care.

This device is a standalone, contamination-resistant (CR) continuous ambulatory peritoneal dialysis (CAPD) system designed for low-resource settings.

This is a miniaturized, magnetically levitated axial flow blood pump designed to provide mechanical circulatory support for children with complex congenital heart defects, particularly those with Fontan circulation.

Telescoping short sheath is designed for pediatric catheterization and electrophysiology procedures. This innovation reduces risks, radiation exposure, and the overall length of the procedure.

NurseAide assists in the safe transfer of neonates in NICUs to enable safer transfers, promoting bonding and neurodevelopmental benefits for preterm and critically ill infants.

Robotic surgical system that allows for minimally invasive procedures with smaller instruments than in currently available systems

AcQumen Medical develops an impedance and ultrasound device with cardiac analytics to improve pediatric urgent care diagnostics.

Altra Infusion has developed an advanced infusion system that addresses key challenges in the infusion industry, such as mechanical failures, flow issues, and false alarms, making it particularly beneficial for specialized units like NICUs and ICUs.

The Pouch Pal is a three-ringed device that enhances neonatal ostomy care by integrating a secure catheter port for efficient, leakproof refeeding.

AVaTAR MedTech has developed a surgical method and set of medical devices designed to reconstruct the aortic or pulmonary valve in children and adults using autologous tissue.

Kalogon is building a bedsore pressure management system designed for Neonatal Intensive Care Units (NICUs).

iFocus Health enables ADHD treatment measurement using a computer webcam, tracking eye movements during daily activities with AI to support data-driven clinical decisions.

The novel CathConnect device is a simple technology to transform the existing standard Foley Catheter into a safe and effective solution.

Auctus Surgical develops novel technologies focusing on non-fusion scoliosis correction allowing for non-surgical dynamic adjustment of implants over time.

CergenX Wave, a FDA breakthrough-designated medical device, leveraging advanced AI to identify newborns at highest risk of brain injury.

Silver-based central line protectors are designed to prevent central line-associated bloodstream infections (CLABSIs)

Lectra Tape offers a solution combining targeted, wireless muscle stimulation with kinesiology tape to provide non-invasive, personalized pain relief.

The FreeArm clamps to surfaces like tables, cribs, and strollers, serving as a travel IV pole with a bendable arm for convenient gravity feeding.

Mu'id Mecca Medical innovates medical devices to enhance care for cleft conditions and improve patient outcomes.

PectusVac is a non-surgical option for the correction of the pectus excavatum condition using negative suction pressure.

A New Endotracheal Tube to Avoid the Asphyxiation of Premature Infants

Intake Breathing is a nasal dilation system that uses external magnetic strips to enhance airflow, improving breathing for sports, sleep, and daily activities.

FreezeNit is an innovative head lice treatment that uses cold CO₂ gas to eliminate lice and nits without the need for messy creams, harmful pesticides, or tedious combing.

ClearCam is a laparoscopic lens-cleaning device that removes debris and fog without requiring scope removal, improving surgical visibility.

Kitea Health is building the next generation of micro-implantable devices (Intracranial pressure (ICP) microsensor) for managing chronic health conditions.

Impaired relaxation (indication of diastolic dysfunction) detection via ECG Intracranial pressure (ICP) microsensor.

IF-based microfluidic leukapheresis devices separate white blood cells (WBC) from whole blood using fluid dynamic principles and the larger size of WBC compared to the other cells. This is achieved without moving components or a driving pump, although one can be used.

The CardiaZn is a bioresorbable stent made of Zinc alloy which is a required dietary supplement, is naturally inflammatory, and has great mechanical performance. The stent has the same radial strength as metal stents, has the right degredation rate for pediatrics, and all elements are safe and biocompatible.

The Canta-S Bone Graft is a bone grafting technology designed to neutralize reactive oxygen species (ROS) that exist at elevated levels in patients with metabolic disorders.

The YourSteps platform includes a web-based therapist portal and a family mobile app. The therapist portal enables remote therapeutic monitoring to overcome time and travel constraints. The family app provides a user-friendly interface with video, audio, and written instructions for effective home-based therapy.

NeurAxis focuses on targeted therapies for the pediatric and adolescent population suffering from disorders of gut-brain interaction (DGBIs).

This pediatric mobile wheelchair enables users with physical impairments to switch from seated to standing positions and move independently while standing. It promotes equity, inclusion, and participation in activities that traditional wheelchairs make challenging.

The innovation is an interactive educational toy called Octo for kids with Congenital Heart Disease (CHD) to learn about their condition (including medical terminology, cardiac anatomy, etc).

Commercially available digital otoscope that attaches directly to clinic handles from Welch Allyn. Unique speculum geometry and built-in touch screen.

Universal platform technology that integrates smart needles to minimize injury during IV insertion for kidney patients and children.

An affordable and easy-to-use electronic stethoscope that pairs with a web app that is accessible on laptop, phone, or tablet devices. The webapp uses augmented reality to show exactly where to position the stethoscope on the patient's body, and then begins sound recording when the device placement is correct.

The Overnight Pediatric Oxygen Delivery (OPOD) System is designed to deliver a consistent, non-contact flow of oxygen to a sleeping pediatric (ages 0-5 YO) patient to reduce the effects of chronic hypoxia without the need for a nasal cannula.

A simulation car enviornment to determine safe discharge of preterm and infants at high-risk for cardiorespiratory compromise. It provides realistic, safe training scenarios for parents, ensuring they are well-prepared to care for their newborns during travel which will enhance infant safety and parental confidence.

This device is a low-cost wearable device combining temperature sensors to detect tissue temperature changes and an alert application system for early detection of IV infiltration in infants. This design improves clinician response time and reduces negative outcomes for the patient.

Current warming techniques are not MRI-compatible, which can cause long-term damage to the MRI, or are not developed for pediatric patients. This device is an MRI-compatible pediatric device that normalizes the temperature of pediatric patients.

Nasogastric suction is used in children for stomach decompression and post-operative care, but high suction levels can cause injury. A solution with a computational model, valve mechanism, internal valve cap, canister lid, and external valve cap regulates pressure, releasing excess pressure through a mechanical feedback mechanism.

Strabismus, a common pediatric ophthalmology issue involving misaligned eyes, often requires surgery. This device will braid extraocular muscle fibers by fastening grouped and separated fibers and guiding them through a braiding pathway using gears and manipulators.

This medical device placed between the pump and oxygenator of the ECMO circuit aims to use acoustic sensing to continuously monitor the clotting capabilities of blood in circulation to assess whether anticoagulant doses must be increased or reduced.

A novel device to detect impending enuresis before unintentional voiding by using Near Infrared (NIR) light.

NeoEar is a silicone splint shaped to gently correct ear deformities during the first weeks of life

3D-printed handle that attaches to a conventional face mask to perform chest physiotherapy.

A novel vaginal dilation device commonly used in adolescent women that utilizes safe and sterlizable polymers as well as incorporated uniform lubrication and automated mechanical expansion.

Mackey Mask is an adhesive free, waterproof, wipeable, and comfortable NG tube securement device. Mackey Mask encases the NG tube on the face and has patent pending halo design for storage of excess tubing.

Aegis Star Dental Technologies has developed Keles Keyless Expander (KKE), which is a rapid palatal expander (dental device) specifically designed for pediatric patients (7-14) by incorporating a novel built-in activation mechanism.

The NeuroBell EEG Monitor offers 8-channel EEG monitoring for automated neonatal seizure detection in real-time, alerting NICU staff for immediate intervention.

HealthSeers is developing an AI-enabled stethoscope-like device to record and detect heart complications in pediatrics

AV Healthcare is developing NasoGuard, a pediatric medical device for safe and accurate nasogastric tube insertion. The device enhances precision, reducing the risk of malpositioning and related respiratory complications during tube placement.

Herald Medical is developing a minimally invasive catheter for suture mediated closure of enterocutaneous fistulae.

Vascudyne is advancing the development of a conduit with the ability to grow with the child, aiming to eliminate the need for multiple operations and the morbidities these produce.

This project supports development of a 3D printed bioabsorbable stent that can be made for this underserved pediatric population.

Bloom Standard is an autonomous, hands-free ultrasound scan for the detection of heart or lung abnormalities in neonates, infants and children, particuarly in under-resourced, humanitarian and font line settings

On-demand compounding of peritoneal dialysis fluid in dialysis centers with limited dialysis access to provide treatment for the pediatric AKI and ESKD patients for whom PD is the only option

Adialante is a compact neurological pediatric MRI system using Frequency-modulated Rabi Encoded Echoes (FREE), to enable the system.

Digital workflow for the fabrication of nasoalveolar molding (NAM) devices

Custom MASK Interfaces to Advance Pediatric Respiratory Support

A working prototype to provide automated chest compressions on infants.

Deep Learning Digital Inline Holography for Real-time Peritonitis Detection

The PAWPER tape is an advanced weight estimation system for children and adolescents. It is easy to use and can rapidly provide estimates of total and ideal body weight. It is designed for emergency care, to be used with a comprehensive drug dosing guide.

PGXL Technologies is developing the Uromarker test for rapid screening of obstructive sleep apnea (OSA) and sleep disordered breathing that may contribute to attention deficit hyperactivity disorder (ADHD) in children.

4WEB Medical’s 3D printed technology utilizes engineering principles such as structural mechanics and adjacent material reaction to produce innovative implants that may actively participate in the healing process.

Ember Sleep is creating the next generation medical device to treat sleep apnea. This device is comfortable, effective, and non-invasive.

Neurastasis is helping patients suffering from acute ischemic stroke to reduce long-term symptoms through neurostimulation.

Integrated Molecular Innovations is developing cutting-edge biowearable devices that continuously monitor hormone levels in the interstitial fluid.

SMOLTAP is an Infant Spinal Tap positioning solution developed to reduce the variability and increase 1st stick spinal tap success rates.

DriQ Health is an intelligent IoT diaper monitoring system for the management of urinary incontinence among adults in long-term care (LTC) and in patients with complex conditions in hospital geriatric departments.

The Periscope aims to reduce the incidence of mucosal trauma during gastrointestinal procedures requiring the use of a duodenoscope (e.g. ERCPs).

Star Harness at University of Arkansas Biodesign is creating a harness for infants with developmental dysplasia of the hip (DDH) that is comfortable, easier for the parents to use, and price comparable to the leading model.

Aurelia Vitals is working on a wireless monitoring system of neonatal vital signs for early warnings for sepsis.

KnovelCam specializes in cutting-edge, compact medical X-ray systems tailored for both human and veterinary applications.

Vascular Perfusion Solutions is working on a perfusion device intended to extend the viability of pediatric hearts longer than the standard of care.

The Sonura Beanie was designed to protect newborns from high-frequency & intensity noise exposure in the NICU while promoting neurodevelopment through the transmission of parental audio messages.

Atrility Medical is developing the AtriAmp which facilitates the monitoring and treatment of atrial arrhythmias by providing a continuous atrial electrogram.

Momentum Health is a digital health platform for remote 3D Management of Scoliosis & Other Deformities.

Advanced Telesensors developed Cardio/i which uses advanced radar technology and proprietary machine learning/artificial intelligence algorithms to sense heart rate and breath rate in real-time, sending alerts when an abnormal event occurs.

Designed as a sippy cup, the EarFlo medical device is designed to non-invasively treat Otitis Media with Effusion (OME) in order to prevent developmental delay earlier and avoid surgery.

PigPug Health is transforming child mental health with AI-powered neurofeedback for kids with ADHD and autism

Hoth Intelligence believes augmented reality will change the future of medicine. They are developing transformative software that improves healthcare for providers, patients, and their loved ones around the world.

AmpliPharm is creating a device that dispenses an accurate dose of solid oral granule medications for pediatric patients.

BioLum Sciences specializes in bioanalytical chemistry & assay development for chronic disease. BioLum's novel chemiluminescence provides a ‘window into the body,’ by measuring biomarkers relating to cardiovascular, respiratory and other inflammatory diseases.

MiraHeart noninvasively monitors central venous pressure, a crucial metric in pediatric heart failure care, for better-informed medication management.

Baby BioSignals developed Miro-Baby Sense which can detect markers of motor delay toward early detection of ASD and neurodevelopmental disorders at home.

SpineX is a clinical-stage bioelectric MedTech company, committed to improving the lives of people with neurological conditions by restoring day-to-day function through non-invasive neuromodulation.

Gabi SmartCare is an AI-powered, cloud-based platform which processes and structures collected data, detects health events, and gives healthcare professionals a real-time, personalized, and predictive health assessment report.

Mendability is a digital platform for Sensory Enrichment Therapy (SET), benefiting patients with developmental disorders.

PortaVision focuses on the unique challenges of caring for fragile, immobile, or remote-location patients that are underserved by traditional mobile C-Arm systems.

Neuro Solutions Group is developing healthcare technology solutions designed to empower children with neurodevelopmental disorders and their parents. Their stand-alone solution, Kairos, provides parental guidance and helps children develop skills while monitoring behavior and medication information.

Tippit is developing an umbilical venous access catheter for infusing fluids.

Deft Medical allows for easier needle placement in any procedure by tracking the needle position against an ultrasound image in real time.

EnOPrep provides a sealed system for safely crushing and dissolving solid medications at the point of care for oral and enteral administration. Medication loss is negligible, and caregivers are protected from airborne drug exposure.

SyNAPS is launching a line of functional headwear for young children with cochlear implants. SyNAPS headwear supports the performance of the cochlear implant by holding the processor(s) in place, enabling uninterrupted access to sound during a child’s most critical period of brain development.

PFRx is developing a portable, easy-to-use, affordable home biofeedback device that captures the patient’s attention through gamification to address the goals of bowel and bladder dysfunction in the privacy of the child’s home.

Hera Biotech is developing and commercializing the world’s 1st non-surgical test for definitive diagnosis and staging of endometriosis.

Advanced Optronics is developing a guidance system for cochlear implantation to improve hearing outcomes.

Longhorn Life Sciences is a MedTech company whose mission is to develop needs-driven medical technology that will improve patient experiences and outcomes.

The Blow By Oxygen Foundation is developing low-cost oxygen delivery systems for children and disabled individuals with pulmonary hypertension.

XN Health is treating diaphragmatic atrophy on patients on ventilators by stimulating the diaphragm

Rx Bandz is a drug delivery platform company that has developed the world's smallest auto-injectors and formulations to save lives around the world.

CurieDx is an AI-based remote screening of strep throat or UTIs for telehealth.

Bivacor is developing a long-term therapy for patients with severe heart failure. It is an implantable artificial heart based on rotary blood-pump technology.

Compact Medical is on a mission to revolutionize bag-valve-masks with the Butterfly BVM, the first BVM designed to be able to precisely deliver adjustable volumes and peak inspiratory pressures to patients of all sizes.

Pedia-Dose is a mobile application that helps parents and caregivers accurately dose over-the-counter medication for their children, track dosing frequency, set dosing reminders at recommended intervals, and track common symptoms of an illness.

Southwest Neuroendovascular Technologies is developing a microcatheter for interventional pediatric neurovascular AVM therapy addressing limitations of current detachable tip microcatheters.

Nen is a digital therapeutic for pain management in pediatric cancer patients.

PeriCor, LLC was founded with the primary mission to provide minimally invasive alternatives to infants, children and adults who require interventions including pacemakers, defibrillators or cardiac ablation procedures.

Solenic Medical Inc. is developing an innovative non-invasive treatment for infected metallic implants in the body.

Gogoband is the first Intelligent bedwetting alarm capable of waking children prior to them wetting themselves.

Anuncia's ReFlow System helps patients with cerebrospinal fluid (CSF) disorders, such as hydrocephalus, that require draining or shunting the CSF.

The TubeClear System, which uses a mechanical method to clear clogged EADs, is comprised of a reusable Control Box paired with a single-use Clearing Stem.

OtoNexus Medical Technologies’ state-of-the-art advanced ultrasound otoscope analyzes the presence and type of effusion so that primary care pediatricians can instantly and accurately assess middle ear infections.

Sunny is a a self care brand that simplifies your period and saves the planet with the Sunny Cup + Applicator. The Sunny Cup + Applicator is the reusable period cup that inserts like a tampon, while combining the sustainable, cost-saving, and body benefits of a period cup.

Blue Comet Medical Solutions LLC is creating a non-invasive, user-friendly medical device to allow a non-clinician to test for the presence of Strep throat.

Luminoah is on a mission to revolutionize the enteral feeding market with a wearable system that combines durable medical equipment, consumable nutrition pouches, and remote patient monitoring to optimize compliance and clinical outcomes.

KidTech is working to develop a safe and highly effective lightweight baby-friendly mobile phototherapy system which allows continuous treatment without interruptions of breastfeeding and parent-child bonding.

EvoEndo is developing a single-use endoscope system enabling completely unsedated upper endoscopy for children and adults.

EpiWatch is an integrated digital health platform for people with epilepsy. They reduce the burden of the disease and provide safety and peace of mind to children and young adults with epilepsy and their caregivers.

The PLEGS device gives children with walking disabilities a low cost, reliable, and easy-to-use assistive and rehabilitation technology that provides walking assistance and gait therapy for use at the clinic and at home.

Lighthanded’s otoscope enables pediatricians to detect OME with up to 90% accuracy, with a simple and low-cost solution.

The Intubation Assist Device assists in LMA-ETT exchange under direct visualization using a fiberoptic scope. There is a critical need in pediatric airways due to their acuity, the smaller size of the airway, and smaller equipment, therefore offering far less margin for error.

Refreshable Biosensors for Continuous Renal Function Monitoring's long-term goal is to transform kidney disease treatment by developing a fully wireless, miniaturized, multifunctional biosensor that can be directly interfaced to a urinary catheter or the internal surface of patient bladder.

Renata is developing an adjustable stent that has been purposefully designed for pediatrics to last a lifetime. The device’s initial size at birth is less than 2 millimeters in diameter and can expand greater than 20 millimeters in diameter as the patient grows.

Epitel’s Epilog is a wearable, wireless, discreet EEG sensor. which enables universal access to medical-grade, remote EEG monitoring.

PREEMIEr Diagnostics' technology will help predict which preterm infants are at risk of glucose-related morbidities (such as retinopathy of prematurity). This will allow for early intervention of glucose control to help prevent such disorders.

Tremedics manufactures a bioresorbable stent, Illusicor, that is designed to treat the coarctation of the aorta and manage aortic growth.

Relavo is changing the way kidney failure patients receive treatment by making home dialysis safer and more accessible.

Glimpse believes that by diagnosing ear exams accurately from home, Glimpse can give moms and kiddos, and society what they deserve.

HERO Medical Technologies is developing a cap-shaped rapidly applied hemorrhage-control HERO “Smart” Bandage and mobile app that leverages artificial intelligence to automate vital signs and patient monitoring.

PhotoniCare has received US FDA clearance for the OtoSight Middle Ear Scope, an ear exam device that uses near-infrared light (optical coherence tomography, or OCT) to uniquely see behind the eardrum, which is vital for accurate diagnosis of ear infections and judicious use of antibiotics.

The Bio-Zipper is a surgical device that reinforces extensive suture lines in LUTR to decrease the total rate of post-operative complications & readmissions by 20%.

Starling Medical is bringing the future of a proactive and predictive home based healthcare system to patients today. They are developing medical devices to improve the lives of chronic care patients by passively monitoring changes in their urine over time with their AI and care team infrastructure.

Prapela is a breakthrough, noninvasive stimulation therapy that naturally improves breathing and oxygenation in newborns.

Spark Biomedical developed the Sparrow Therapy System™ — the first FDA-cleared, drug-free, personalized, wearable solution for opioid withdrawal relief backed by evidence from a double-blind, randomized controlled clinical trial targeting patients with opioid use disorder.

Rhaeos is developing a FlowSense device, a wearable non-invasive patch that looks like a bandage and which can provide data on flow through a shunt.

PyrAmes is developing the Boppli®, a FDA 510(k) cleared wearable medical device for continuously & non-invasively monitoring blood pressure for critically-ill infants.

Invictus is developing the Neoasis accessory to reduce noise levels within an infant incubator in the NICU.

Vax-Immune Diagnostics' LabReady’s Enriched Specimen Transport ™ is a radical new way to diagnose infections faster, more accurately, in the lab, at the point of care, and soon the home.

Trexo Robotics provides wearable robotic gait-training for children with disabilities, enabling them to experience walking in a stable and independent way, leading to improved physical, cardiovascular, respiratory, and digestive function, as well as enhanced quality of life.

Abilitech Medical creates assistive devices to aid those with upper-limb neuromuscular conditions or injuries in functional activities associated with home, community, and work. The Abilitech™ Assist helps people use their arms to live more independently and complete activities of daily living.

Cystomanometer and Cystoelastometer monitors at-home bladder pressures +/- bladder volumes in patients using catheterization for their neurogenic bladder. This will result in improved health care and prevention of kidney and bladder damage.

Global Continence has developed a novel technology that intercepts a bedwetting (enuresis) episode with transcutaneous nerve stimulation (TENS) methodology that overrides and curtails the episode with a neuromodulation signal.

Noninvasix recognized that there are no continuous, non-invasive vital signs monitors of the right side of the heart. They will be first to non-invasively monitor central venous saturation and the severity of sepsis and septic shock, enabling clinicians to diagnose and monitor the response to treatment of tissue hypoxia in real-time.

Strados Labs is developing RESP™ Biosensor, a revolutionary wearable lung sound sensor and AI-enabled monitoring solution. It is the first FDA-cleared device to remotely capture lung sounds, tracking respiration rate, heart rate, activity, and sleep quality.

HerStent is a novel degradable & resorbable vaginal stent designed to prevent vaginal fibrosis following surgery for female adolescent patients & post-radiation vaginal stenosis for adult patients.

CorInnova is developing a non-blood contacting cardiac assist device for heart failure, scalable for smaller hearts. It deploys within the pericardial sac, gently compressing the heart, increasing output and promoting heart recovery.

PolyVascular’s aim is to transform the care of children with congenital heart disease by developing an entirely new generation of valves made of medical-grade polymer devoid of any biological tissue and extending the time between open-heart surgeries.